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More serious disorders occur when the virus infects and damages the eye (herpes keratitis), or invades the central nervous system, damaging the brain (herpes encephalitis).People with immature or suppressed immune systems, such as newborns, transplant recipients, or people with AIDS, are prone to severe complications from HSV infections.Kilmer famously came head to head with director Joel Schumacher, who told him that his poor treatment of the crew was unacceptable.Long ago, Val Kilmer was a promising actor in the Hollywood arena.Furthermore, there are all those ex-wives and ex-lovers who have gone on the record to let everybody know how crazy this guy can be.His most famous outburst happened during the making of Batman Forever, where Kilmer allegedly had a very serious fight with Joel Schumacher.Many people infected with HSV-2 display no physical symptoms—individuals with no symptoms are described as asymptomatic or as having subclinical herpes.Herpes whitlow is a painful infection that typically affects the fingers or thumbs.

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HSV is the most common cause of viral encephalitis.In the presence of a certain gene variation (APOE-epsilon4 allele carriers), HSV-1 appears to be particularly damaging to the nervous system and increases one's risk of developing Alzheimer's disease.The virus interacts with the components and receptors of lipoproteins, which may lead to its development.HSV infection has also been associated with cognitive deficits of bipolar disorder, and Alzheimer's disease, although this is often dependent on the genetics of the infected person.In all cases, HSV is never removed from the body by the immune system.

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